5 Best Parasite Cleanses For Women Over 45

Rootmeadow blew us away and was our favorite for women over 45. The drops contain seven globally sourced ingredients formulated to do four things every other cleanse on this list fails to do at the same time: penetrate the biofilm shield, target parasites at every life stage including the eggs, flush the dead organisms before they release toxins inside the body, and address the bacterial and fungal overgrowth that almost every cleanse ignores completely.

We loved the formula. Wild Mediterranean wormwood, Appalachian black walnut, Indonesian clove, Hungarian pumpkin seed, Brazilian soursop leaf, Greek oregano oil, and aged Japanese garlic. The wild Mediterranean wormwood is what sets Rootmeadow apart. In 2015 the Nobel Prize in Medicine was awarded for research isolating the active compound in wormwood, and the wild Mediterranean variety is prized for a far higher concentration of that compound than the cultivated farm version most Amazon brands use. Rootmeadow only uses the wild variety. None of the others on this list do.

The reviews from women in their late 40s, 50s and 60s keep repeating the same pattern: the bloating eases first, then the sleep, then the energy. Rootmeadow also backs every order with a 90 day money back guarantee, so the risk of trying it sits with them, not with you.

Simply put, Rootmeadow was my favorite formula. It is the only one on this list built around the wild Nobel Prize wormwood variety, and the only one that addresses all four problems at once.

We thought Zahler ParaGuard was a decent option for women who want a slightly more affordable starting point. The formula has many of the standard antiparasitic ingredients you would expect, including wormwood, black walnut hull, garlic, clove, and pumpkin seed, and we liked the addition of marshmallow root and slippery elm for soothing the gut lining. However, the wormwood used is the standard cultivated variety, not the wild Mediterranean variety, and the formula does not address the biofilm shield or the co-infections that come with chronic parasitic infection. As a result, Zahler ParaGuard earned our number 2 spot.

We loved that Go Nutrients Intestinal Edge is non-GMO, vegan, and alcohol-free. The formula did a good job cleansing the gut, and the addition of orange peel and lavender flower makes the taste more palatable than most of the others we tried. However, the formula contains pennyroyal and tansy, two aggressive antiparasitic herbs that carry safety concerns for women over 45, particularly those with liver issues or on multiple medications. It cleanses effectively, but it does not solve the full four-problem puzzle, so we put this at number three on our list.

Peak Performance is the only USDA Organic certified product on this list, which is appealing to those of us in the clean-living demographic. The formula contains organic wormwood, organic black walnut, organic clove bud, organic pumpkin seed, and organic artichoke — a nice addition for liver support. However, it is missing the soursop leaf, the oregano oil for the biofilm shield, and any ingredient for the bacterial and fungal overgrowth that so often shows up alongside a parasitic infection. The wormwood is also the cultivated organic variety rather than the wild Mediterranean one, so it earned the number 4 spot on our list.

Nature's Answer has been around for several decades and has real name-brand recognition. We love that it is alcohol-free and offers a classic, time-tested traditional herbal combination. Two things held it back. First, the formula only contains four ingredients: clove, black walnut, sweet annie, and wormwood — not enough to address the four-problem framework of chronic parasitic infection in women over 45. Second, the bottle is only 1 fl oz, which means a single bottle does not last long enough for the full eight-week protocol most women need to actually break the parasitic cycle. As a result, Nature's Answer ended up fifth on our list.